Campy Protons have been the BEST wheels I have ever owned...
At 220 lbs., I am not 100% sure how they would hold up for you. I weigh 158 on a good day and 165 at the max. One set of my Protons has over 15k on them without any need for adjustments, only occasional lube. They have been ridden in the harshest conditions including numerous excursions on dirt, gravel, old brick (cobble-like) and typical Texas chip-seal roads without ever missing a beat or going out of true.
At your weight, I would definitely consider a handbuilt set of Ultegra/DA - Open Pro wheels with 32 spokes front and rear. Well under $500 there. Not fancy, but very very functional and plenty strong.