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Is Shimano's E-thru-axle the same as other 12x100 or 12x142 through axle skewers? Or is there something different about it?
 

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Possibly but keep in mind that despite a bike having 12x100 and 12x142 thru axles, but as I found out, there are several standards as Rock Shox, Scott, and Shimano have different thread pitch which prevents interchangeability. Also, I found that 12x142 road thru-axles from Carbon-Ti and Extralite were nearly 1-cm longer front and rear than my bikes spacing.
 

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Adorable Furry Hombre
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Nope. The axle has a captive replaceable nut and uses an enclosed can like Shimano quick release.
 

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12mm through-axles come in three different thread pitches. Shimano (also called E-thru) is 1.5mm. Maxle is different.
 
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