I tried to size up a road bike today since mine is too large. I'm 5'5" with a 28" inseam and they put me on a size 50. Anyway I noticed the wheels were 26" instead of the standard 700cc (28"). They told me the 700's would be too big for such a small frame but I can't imagine Iban Mayo (the small basque rider?) riding in the tour de france with such a disadvantage and able to crack lance in the mountains.